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Plantar warts treated with topical adapalene
1Senior Consultant Dermatologist, Indraprastha Apollo Hospital, New Delhi - 110074, India.
Indian Journal of Dermatology
|November 29, 2011
Summary
Topical adapalene gel with occlusion offers an effective treatment for plantar warts caused by human papilloma virus (HPV). This method demonstrated faster clearance times and no adverse effects in a pilot study.
Area of Science:
- Dermatology
- Virology
- Pharmacology
Background:
- Plantar warts, caused by human papilloma virus (HPV) types 1, 2, and 4, present a significant therapeutic challenge.
- Existing treatment options for plantar warts have shown variable success rates.
Purpose of the Study:
- To evaluate the efficacy of topical adapalene with occlusion for treating plantar warts.
Main Methods:
- An open study included 10 patients with a total of 118 plantar warts.
- Treatment involved weekly application of 0.1% adapalene gel, with occlusive polythene dressing.
- Wart clearance was assessed weekly.
Main Results:
- All plantar warts (118) in 10 patients cleared within an average of 39±15.07 days.
- No adverse effects such as scarring, irritation, erythema, or infection were observed.
Conclusions:
- Topical adapalene with occlusion provides a rapid and safe treatment for plantar warts.
- Further trials with larger patient cohorts are recommended to confirm these findings.
