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Childhood diarrhoea: failing conventional measures, what next?
Faraj Alkizim1, Duncan Matheka, Anne Muriithi
1Department of Medical Physiology, University of Nairobi.
Insights
Infant diarrhea remains a major global health challenge, contributing significantly to child mortality and hindering progress toward Millennium Development Goal 4. Improved prevention and treatment strategies are crucial.
Area of Science:
- Pediatrics
- Global Health
- Public Health
Background:
- Diarrhoea is a primary cause of infant mortality globally.
- It significantly impacts the achievement of Millennium Development Goal 4 (MDG-4), which aims to reduce child mortality.
- The article examines the role of diarrhoea in infant mortality and its implications for MDG-4.
Purpose of the Study:
- To analyze the contribution of infant diarrhoea to child mortality rates.
- To review current strategies for diarrhoea prevention and management.
- To assess progress towards Millennium Development Goal 4 in light of diarrhoeal disease burden.
Main Methods:
- A comprehensive literature search was conducted on PubMed.
- Keywords included "acute infant diarrhea," "prevalence," "management," and "prevention."
- 23 relevant articles were selected from 634 retrieved studies for detailed review.
Main Results:
- Diarrhoea is the second leading cause of infant mortality worldwide, with 1.5 million deaths annually.
- Consequences include dehydration, malnutrition, shock, and long-term diminished cognitive function and school performance.
- Oral Rehydration Therapy is the primary treatment, though compliance varies. Zinc supplementation, immunization, and hygiene are also key interventions.
Conclusions:
- Minimal progress has been made towards MDG-4's goal of reducing childhood mortality by two-thirds by 2015.
- Existing diarrhoea control strategies require review and enhancement.
- Research focus should broaden beyond high-profile diseases to address the substantial daily burden of diarrhoeal diseases in children.
Background:
Diarrhoea is one of the leading causes of infant mortality. This article analyzes its contribution towards the realization of millennium development goal number 4 (MDG-4).
Methods:
A PubMed search using keywords acute infant diarrhea together with prevalence, management, or prevention 23 of the 634 generated articles were reviewed for inclusion.
Results:
WHO first expressed concern about diarrhoeal mortality in 1979. Two decades later it reported diarrhoea as the second leading cause of infant mortality worldwide. The annual death toll of 1.5 million is greater than AIDS, malaria and measles combined. Short term repercussions (dehydration, electrolyte imbalance, malnutrition, shock, death) plus long-term diminished fitness index, cognitive function, and school performance have major impact on society. Ever since its 1971 success, Oral Rehydration Therapy has been the cornerstone treatment of diarrhoea. Decreased compliance has been recorded worldwide with Kenya ranking first. Intravenous therapy is useful in preventing complications while anti-diarrhoeals and anti-microbials, are indicated in severe cases. Zinc supplementation has also proven effective, and is recommended along with rehydration. Furthermore, immunization and good hygiene prevent faecal-oral transmissions.
Conclusion:
MDG-4 aims to reduce childhood mortality by 2/3 by 2015. Studies, however, show minimal progress, and the target is likely to be missed. Efforts must therefore be made to review existing strategies and formulate newer ones. Research priorities need to move away from perceived 'killer diseases' since far more children die in a day than have ever died from avian influenza for example.
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