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Updated: May 27, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
Published on: September 18, 2013
Cruciferous vegetables intake and risk of prostate cancer: a meta-analysis
1Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Objective:
To evaluate the relationship between cruciferous vegetables intake and risk of prostate cancer.
Methods:
A systematic literature search up to June 2011 was carried out in PubMed, and the references of retrieved articles were screened. The summary relative risks with 95% confidence interval for the highest versus the lowest intake of cruciferous vegetables were calculated. Heterogeneity and publication bias were also evaluated.
Results:
Seven cohort and six population-based case-control studies met the inclusion criteria of the meta-analysis. A significantly decreased prostate cancer risk was observed overall in the cruciferous vegetables intake group (relative risks = 0.90; 95% confidence interval 0.85-0.96) and the subgroup of case-control studies (relative risks = 0.79; 95% confidence interval 0.69-0.89), but not in cohort studies (relative risks = 0.95; 95% confidence interval 0.88-1.02). No heterogeneity and publication bias were detected across studies.
Conclusion:
Cruciferous vegetables intake is related to the decreased risk of prostate cancer. Because of the limited number of studies, further prospective studies are needed to explore the protective effect of cruciferous vegetables on prostate cancer.
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