Relative endurance of unipolar depression treatment effects: longitudinal follow-up

This study represents a 2.25-year follow-up to a treatment study reported earlier (McLean & Hakstian, 1979) in which 121 unipolar depressed outpatients were treated by either (a) nondirective psychotherapy, (b) behavior therapy, (c) pharmacotherapy, or (d) relaxation therapy. A nondepressed, normal control group was evaluated on the same 28 measures and 6 intervals for contrast purposes. Behavior therapy patients alone were significantly improved in the areas of mood, personal productivity, and social activity, relative to treatment control patients over the follow-up period. Also, twice as many behavior therapy patients (i.e., 64%) fell within one standard deviation of the normal, nondepressed control group distribution on depressed mood, compared with non-directive psychotherapy and pharmacotherapy patients, when scores were aggregated across the 6 assessment points.