Two successful pregnancies in a patient with chemotherapy-induced ovarian failure while on hormone replacement
1Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon. gg02@aub.edu.lb
Abstract:
Chemotherapeutic agents administered for the treatment of malignancies can result in the incidence of premature ovarian failure (POF). Ovarian failure is reflected by elevated serum follicle-stimulating hormone (FSH) levels that may reach menopausal levels, at which the chances of a pregnancy are considered extremely rare. We report a case of a 26-year-old female who experienced two successful pregnancies, despite her diagnosis with chemotherapy-induced POF. This case suggests that patients who suffer from POF secondary to chemotherapy might still retain enough ovarian function with good quality oocytes that could support a healthy pregnancy.
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