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Updated: Aug 11, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Impaired renal function due to raised intraabdominal pressure
1University Department of Surgery, Royal Perth Hospital, Western Australia.
Abstract:
A 19-year-old male developed renal failure after a laparotomy for liver trauma (urinary output of 30 ml/h, plasma creatinine 220 mumol/l). Surgical decompression of the abdomen was performed without any attempt at correcting the underlying pathology. This reduced the intraabdominal pressure (IAP) from 40 to 24 cm H2O and resulted in a massive diuresis (530 ml/h). Twenty-four hours later the plasma creatinine peaked at 280 mumol/l and then returned to within the normal range. This case report confirms that there is a direct relationship between IAP and renal function.
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