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A Tuberculosis Molecular Bacterial Load Assay (TB-MBLA)
Published on: April 30, 2020
Tuberculosis in UK cities: workload and effectiveness of tuberculosis control programmes.
Graham H Bothamley1, Michelle E Kruijshaar, Heinke Kunst
1Homerton University Hospital, London, UK. graham.bothamley@homerton.nhs.uk
BMC Public Health
|November 30, 2011
Summary
Implementing national tuberculosis (TB) control targets requires sufficient specialist nurses. Inadequate resources and fewer nurses correlated with higher TB incidence and treatment loss to follow-up.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Control
Background:
- Tuberculosis (TB) incidence has risen in the UK, prompting national control targets and interventions.
- The study aimed to assess the implementation and effectiveness of these TB control measures.
Purpose of the Study:
- To evaluate the implementation status of national TB control strategies in the UK.
- To determine the effectiveness of these interventions in reducing TB cases.
- To identify factors influencing TB control program success.
Main Methods:
- Utilized enhanced surveillance and clinic data for epidemiological analysis.
- Collected qualitative data from primary care trusts and TB clinics regarding local TB incidence changes.
- Compared local TB control efforts against national TB plan targets and audit data.
Main Results:
- Data access for planning varied significantly (0-22 months).
- Achievement of national targets correlated with increased workload for commissioning organizations (R = 0.8, P < 0.01) but not clinic numbers.
- Cities failing to meet nurse-to-notification ratios had higher treatment loss to follow-up (>6%) and less screening/outreach.
Conclusions:
- Effective TB control programs are contingent upon adequate numbers of specialist TB nurses for early detection and patient management.
- Resource allocation and staffing levels, particularly specialist nurses, are critical for successful TB case-holding and reducing incidence.
- Key elements for TB control include direct referral pathways, primary care sputum collection, and outreach services.
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