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Updated: May 27, 2026

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
Tracer monitored titrations: measurement of dissolved oxygen
Todd Martz1, Yuichiro Takeshita, Rebecca Rolph
1University of California, San Diego, Scripps Institution of Oceanography, La Jolla, California 92093, USA. trmartz@ucsd.edu
Abstract:
The tracer monitored titration (TMT) technique is evaluated for measurement of dissolved oxygen. The TMT developed in this work uses a simple apparatus consisting of a low-precision pump for titrant delivery and an optical detector based on a white LED and two photodiodes with interference filters. It is shown that the classic Winkler method can be made free of routine volumetric and gravimetric measurements by application of TMT theory, which allows tracking the amounts of titrant and sample using a chemical tracer. The measurement precision of the prototype setup was 0.3% RSD.
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