Related Experiment Video
Updated: May 27, 2026

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
Published on: December 20, 2024
Effect of fluoride gels on occlusal fissures in primary molars: an in vitro study
M C Ferreira1, M C M Calvo, R S Vieira
1Department of Health Sciences, Universidale Federal dos Vales do Jequitinhonha e Mucuri, Brazil. meirecofe@ig.com.br
Aim:
To assess the effect of the application of fluoride gels on the acid resistance of occlusal enamel in primary molars.
Study Design:
Forty-five primary second molars were randomly assigned to three groups: a) control (pH-cycling); b) 2% NaF gel/pH-cycling; and c) 1.23% APF gel/pH-cycling.
Methods:
Specimens were longitudinally sectioned in the buccal-lingual direction and used for cross-sectional microhardness testing. Knoop hardness values were converted into vol.% mineral and mineral loss (ΔZ) was then calculated.
Statistics:
The response variables were vol.% mineral and ΔZ. Data were tested using parametric tests at a significance level of 5%.
Results:
No statistically significant differences were found between groups regarding vol.% mineral or ΔZ.
Conclusions:
A single application of a high concentration fluoride compound does not promote greater resistance to demineralisation in enamel pits and fissures, regardless of the product used.
