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Ischemic stroke after recombinant factor VIIa treatment in acquired hemophilia A patient

Abdullah Katgi1, Pinar Ataca, Selda Kahraman

  • 1Department of Hematology, Dokuz Eylul University, Izmir, Turkey. drakatgi@gmail.com

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|November 30, 2011
PubMed

Acquired hemophilia is a rare, life-threatening coagulopathy in adults caused by the development of autoantibodies against factor VIII. Bypass agents such as recombinant factor VIIa (rFVIIa) are usually preferred for bleeding control; however, thromboembolic complications may occur. We report here a case that presented with extensive cutaneous and mucosal bleedings due to factor VIII inhibitors and was treated successfully with rFVIIa and steroid therapy, but was complicated with a life-threatening thromboembolic attack during follow-up.

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