Related Experiment Video
Updated: May 27, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Central line "attention" is their best prevention.
Tammy Kime1, Khawar Mohsini, Martin U Nwankwo
1Covenant Healthcare, Saginaw, Michigan, USA. trkime@yahoo.com
Implementing standardized central line care in a neonatal intensive care unit (NICU) significantly reduced central line-associated blood stream infections (CLABSI). This initiative improved patient outcomes and adherence to best practices.
Area of Science:
- Healthcare Quality Improvement
- Infection Prevention and Control
- Neonatal Intensive Care
Background:
- Central line-associated blood stream infections (CLABSI) increase patient morbidity, mortality, and healthcare costs.
- A Level III neonatal intensive care unit (NICU) experienced a rise in CLABSI rates in 2009.
- Lack of standardized central line management practices preceded the initiative.
Purpose of the Study:
- To evaluate the impact of a standardized central line management initiative on CLABSI rates in a NICU.
- To assess changes in length of stay and adherence to new policies.
- To identify risk factors associated with CLABSI in the NICU population.
Main Methods:
- Retrospective review of CLABSI incidence six months before and three months after policy implementation.
- Phased implementation of standardized practices: hand hygiene, "scrub the hub", tubing changes, and insertion/removal/dressing protocols.
- Measurement of CLABSI incidence, length of stay, and policy adherence.
Main Results:
- Clinically significant reduction in CLABSI rate from 15.6% per 1000 line days to 0% in 2010.
- Increased adherence to standardized central line care policies.
- Identified a correlation: each additional week of patient stay increased CLABSI risk sevenfold.
Conclusions:
- Standardized central line management is effective in reducing CLABSI in NICU settings.
- Adherence to best practices significantly mitigates infection risk and improves patient safety.
- Multifaceted approach involving hand hygiene and line care protocols is crucial for infection control.
Related Concept Videos
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Endocarditis IV: Nursing Management
Preventive Healthcare Services
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

