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Updated: May 27, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
[Sickle cell disease: from molecular aspects to clinical practice. A case report and a literature analysis]
Sophie Huynh-Moynot1, Jean-Clair Moynot, Diane Commandeur
1Fédération d'anesthésie-réanimation et des urgences. sophiehuynh@gmail.com
Abstract:
Sickle cell disease is the genetic disease most frequently detected at birth in France. The comprehension and knowledge of its pathophysiology allow to establish the principles of management for the drepanocytic patient, especially in the perioperative phase. In the light of recent recommendations published for anesthesia of a drepanocytic adult, this clinical case revealed allows to reexamine that subject, with a focus on biological aspects, which are transfusional strategy and antibioprophylaxy. The presented observation is a concrete feature of daily collaboration between clinician and biologist, which is an essential point of the ISO standard EN 15189 concerning laboratories' accreditation.
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