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Stop task after-effects in schizophrenia: behavioral control adjustments and repetition priming
Peter G Enticott1, Daniel J Upton, John L Bradshaw
1School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia. peter.enticott@monash.edu
Neurocase
|November 30, 2011
Summary
Individuals with schizophrenia exhibit reduced behavioral adjustments after failed response inhibition, indicating potential issues with error detection but not repetition priming.
Area of Science:
- Cognitive Neuroscience
- Psychiatry
- Neuropsychology
Background:
- Stop-task after-effects, including slowed response times, reflect response inhibition and may indicate behavioral control adjustments and repetition priming.
- Schizophrenia is a complex disorder often associated with cognitive deficits, including impairments in executive functions like inhibitory control.
Purpose of the Study:
- To investigate stop-task after-effects in patients with schizophrenia compared to healthy controls.
- To examine behavioral control adjustments and repetition priming following response inhibition in schizophrenia.
Main Methods:
- Participants (schizophrenia patients and healthy controls) completed a stop-task.
- Responses to the go signal were analyzed based on the preceding trial's characteristics, specifically focusing on inhibition success or failure.
Main Results:
- Schizophrenia was associated with significantly reduced response slowing after unsuccessful response inhibition compared to controls.
- No evidence of impaired repetition priming was found in patients with schizophrenia.
Conclusions:
- The findings support neurocognitive models suggesting reduced behavioral adjustments and possibly impaired error detection in schizophrenia.
- Results challenge current retrieval-based repetition priming accounts of cognitive function in schizophrenia.
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