Related Experiment Video
Updated: May 27, 2026
06:45
Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
[Lympho-venous shunts and thromboids in urinary obstruction]
1kohlmann@pathologie-vechta.de
Der Pathologe
|November 30, 2011
Summary
Early urinary obstruction shows tissue reactions to urine leakage, with Tamm-Horsfall protein acting like a foreign body. This leads to drainage via renal lymphatics and shunts, potentially causing severe kidney impairment.
Area of Science:
- Nephrology
- Urology
- Pathology
Background:
- Urinary obstruction can lead to significant renal complications.
- Understanding early tissue responses to urine extravasation is crucial for managing kidney injury.
Observation:
- A case of urinary obstruction revealed rapid tissue reactions to extravasated urine.
- Tamm-Horsfall protein was observed to organize as a foreign body-like substance.
Findings:
- Extravasated urine and Tamm-Horsfall protein were drained via dilated renal lymphatics and lymphovenous shunts.
- Polypoid formations, termed thromboids, with potential vessel obliteration were identified.
Implications:
- These findings highlight a novel pathway for urine and protein drainage in obstruction.
- The observed thromboid formations may contribute to severe renal impairment and kidney damage.
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