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Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

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Functional and morphological differences following Monarc and TVT-O procedures.

W-C Huang¹, S-H Yang, J-M Yang

¹Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology

|November 30, 2011

Summary

Both Monarc and TVT-O procedures offer comparable outcomes for treating urodynamic stress incontinence (USI). Short-term follow-up shows similar functional results and ultrasound-assessed tape and urethra morphology for both surgical tape placements.

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Area of Science:

Urology
Gynecology
Pelvic Floor Surgery

Background:

Urodynamic stress incontinence (USI) significantly impacts women's quality of life.
Suburethral tape placement is a common surgical intervention for USI.
Comparing different tape systems, such as Monarc and TVT-O, is crucial for optimizing patient care.

Purpose of the Study:

To compare the functional outcomes and morphological changes of the lower urinary tract after Monarc versus TVT-O suburethral tape placement for USI.
To evaluate tape position, tension, and urethral mobility using 4D ultrasound post-surgery.

Main Methods:

Prospective study involving women undergoing Monarc or TVT-O procedures for USI.
Pre- and post-operative assessments included validated questionnaires (SISI, IBS, ISS, UDI-6, IIQ-7), physical examination, cough stress test, and 4D ultrasound.
Primary outcome: clinical assessment responses; Secondary outcome: ultrasound findings.

Main Results:

Both Monarc and TVT-O procedures showed significant improvements in all patient-reported outcome measures.
At 3-month follow-up, success rates and symptom scores were similar between the two groups.
Ultrasound parameters (tape location, tension, urethral mobility) were comparable between Monarc and TVT-O, with similar incidences of postoperative voiding difficulties and overactive bladder symptoms.

Conclusions:

Monarc and TVT-O suburethral tape procedures demonstrate comparable short-term efficacy for USI.
Both methods result in similar functional lower urinary tract outcomes and tape/urethra morphology on ultrasound.
These findings support the interchangeability of Monarc and TVT-O in clinical practice for USI treatment.