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Feed-control development for succinic acid production with Anaerobiospirillum succiniciproducens
Karlheinz Bretz1, Stephan Kabasci
1Fraunhofer Institute for Environmental, Safety, and Energy Technology UMSICHT, Business Unit Renewable Resources, Oberhausen, Germany. karlheinz.bretz@umsicht.fraunhofer.de
Abstract:
The aim of this work was the development of a feed-control for a succinic acid production fed-batch process. The performed batch trials indicated a correlation between succinic acid production and base consumption pH control. Based on the metabolism of Anaerobiospirillum succiniciproducens, a theoretical correlation between base consumption and glucose feed was established and proved in cultivation trials. With the established fed-batch process, the succinic acid yield could be increased to 0.875 (g/g glucose) in comparison to batch processes (0.60) with similar glucose concentrations. Additionally, the results indicate that the osmolarity of the medium has a significant influence on succinic acid production.
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