Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding Processing-Structure-Property Relationships in Spun Spidroin-Mimetic Fibers Using Molecular Dynamics Simulation.

Biomacromolecules·2026
Same author

Corrigendum to "In-line spectroscopic measurement of pH profiles using methyl orange: Application to pH transients in protein A chromatography" [Journal of Chromatography A 1782 (2026) 467106].

Journal of chromatography. A·2026
Same author

In-line spectroscopic measurement of pH profiles using methyl orange: Application to pH transients in protein A chromatography.

Journal of chromatography. A·2026
Same author

Efficient Second-Harmonic Generation from Molecular Monolayers.

ACS nano·2026
Same author

Nonionic peptide amphiphiles and their supramolecular co-assemblies tune charge density and bioactivity.

Journal of materials chemistry. B·2026
Same author

Nitric Oxide-releasing Nanofibers Prevent Restenosis After Arterial Injury in a Renal Failure Model.

The Journal of surgical research·2026

Related Experiment Video

Updated: May 27, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Peptide Self-Assembly for Crafting Functional Biological Materials.

John B Matson1, R Helen Zha, Samuel I Stupp

  • 1Institute for BioNanotechnology in Medicine, Northwestern University, Chicago, IL 60611, USA.

Current Opinion in Solid State & Materials Science
|November 30, 2011
PubMed
Summary

Self-assembling peptide biomaterials offer advanced solutions for tissue regeneration. These peptide-based gels and membranes show promise in treating bone, cartilage, and central nervous system injuries, alongside wound healing and other therapies.

More Related Videos

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Fabrication and Characterization of Colorectal Cancer Organoids from SW1222 Cell Line in Ultrashort Self-Assembling Peptide Matrix
10:23

Fabrication and Characterization of Colorectal Cancer Organoids from SW1222 Cell Line in Ultrashort Self-Assembling Peptide Matrix

Published on: May 3, 2024

Related Experiment Videos

Last Updated: May 27, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Fabrication and Characterization of Colorectal Cancer Organoids from SW1222 Cell Line in Ultrashort Self-Assembling Peptide Matrix
10:23

Fabrication and Characterization of Colorectal Cancer Organoids from SW1222 Cell Line in Ultrashort Self-Assembling Peptide Matrix

Published on: May 3, 2024

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Nanotechnology

Background:

  • Self-assembling peptide scaffolds are promising biomaterials for regenerative medicine due to their biocompatibility and cell signaling properties.
  • Hierarchically-structured constructs are being developed by combining peptide nanostructures with natural biopolymers.
  • These advanced materials hold potential for diverse therapeutic applications.

Purpose of the Study:

  • To review recent advancements in peptide-based gels and membranes for regenerative medicine.
  • To highlight the applications of these peptide materials in various therapeutic areas.
  • To showcase the potential of peptide nanostructures in combination with biopolymers.

Main Methods:

  • Review of recent scientific literature on peptide-based biomaterials.
  • Focus on self-assembling peptide nanostructures and their complexation with biopolymers.
  • Analysis of applications in tissue regeneration and therapeutic interventions.

Main Results:

  • Peptide-based materials demonstrate significant potential in regenerating bone, enamel, cartilage, and the central nervous system.
  • Applications extend to islet transplantation, wound healing, cardiovascular therapies, and erectile dysfunction treatment.
  • Hierarchical structures formed by peptide-biopolymer complexes show promise for advanced biomedical applications.

Conclusions:

  • Peptide-based gels and membranes represent a significant frontier in biomaterials for regenerative medicine.
  • The versatility of these materials supports a wide range of therapeutic strategies.
  • Continued research into peptide self-assembly and biopolymer complexation will drive future innovations.