Related Experiment Video

Updated: May 27, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

Simultaneous total occlusion of multiple distal coronary arteries in acute myocardial infarction

Won-Jun Song1, Ja-Kyung Koo, Kyoung-Ha Park

  • 1Cardiovascular Division, Department of Internal Medicine, Hallym University Medical Center, Seoul, Korea.

Korean Circulation Journal
|November 30, 2011
PubMed

Insights

Multiple coronary artery thrombosis is a rare but serious complication of ST segment elevation myocardial infarction (STEMI). Prompt treatment with thrombus aspiration and antiplatelet therapy can be effective in managing these critical cases.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Emergency Medicine

Background:

  • ST segment elevation myocardial infarction (STEMI) typically involves single coronary artery occlusion.
  • Simultaneous multiple coronary artery thrombosis is an uncommon and often fatal presentation of STEMI.

Purpose of the Study:

  • To report a rare case of STEMI with multiple distal coronary artery occlusions.
  • To highlight the successful management of this critical condition.

Main Methods:

  • Emergency coronary angiography was performed.
  • Thrombus aspiration was utilized for the distal left anterior descending artery (dLAD).
  • Systemic glycoprotein IIb/IIIa inhibitor therapy was administered.

Main Results:

  • The patient presented with multiple ST segment elevations on electrocardiography.
  • Total occlusions were identified in the dLAD, second, and third obtuse marginal arteries.
  • Successful treatment was achieved with thrombus aspiration and glycoprotein IIb/IIIa inhibition.

Conclusions:

  • Multiple coronary thromboses in STEMI are unusual and carry a high fatality rate.
  • Assertive thrombus aspiration and antiplatelet therapy demonstrate efficacy in STEMI patients with multiple distal coronary occlusions.

Keywords:
Coronary artery diseaseMultipleMyocardial infarction

More Related Videos

Optimization of the Longa Middle Cerebral Artery Occlusion Method for Complete Reperfusion13:18

Optimization of the Longa Middle Cerebral Artery Occlusion Method for Complete Reperfusion

Published on: November 22, 2024

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...