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Updated: May 27, 2026

TMS: Using the Theta-Burst Protocol to Explore Mechanism of Plasticity in Individuals with Fragile X Syndrome and Autism
Published on: December 28, 2010
Behavioral intervention for problem behavior in children with fragile X syndrome
Lauren J Moskowitz1, Edward G Carr, V Mark Durand
1Stony Brook University, NY, USA. ljmoskowitz@notes.cc.sunysb.edu
Behavioral interventions significantly reduced problem behaviors and improved quality of life for children with fragile X syndrome. This study highlights the effectiveness of tailored strategies for families facing these challenges.
Area of Science:
- Child Psychology
- Developmental Disabilities
- Behavioral Science
Background:
- Problem behavior is a primary concern for children with fragile X syndrome.
- Fragile X syndrome impacts children's behavior and family quality of life.
- Effective interventions are needed to address behavioral challenges in fragile X syndrome.
Observation:
- This study investigated the impact of behaviorally based interventions on problem behavior and quality of life.
- A multiple baseline design was employed to assess intervention effectiveness in specific contexts.
- Interventions focused on teaching coping strategies for parents and children.
Findings:
- Behavioral interventions led to substantial reductions in problem behavior.
- Family quality of life significantly improved following the interventions.
- The study demonstrated positive outcomes in contexts like bedtime, errands, and toileting.
Implications:
- Behavioral interventions are effective for managing problem behavior in fragile X syndrome.
- These interventions can enhance the quality of life for affected children and their families.
- Findings support the integration of evidence-based behavioral strategies in clinical practice.
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Published on: September 16, 2019
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