Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Updated recommendations for the treatment of light-chain amyloidosis from the Swiss Amyloidosis Network.

Swiss medical weekly·2025
Same author

Unanticipated Global Emergence of Multiple <i>Pneumocystis jirovecii</i> Mutants Selected by Mycophenolic Acid Driving Increasing Outbreaks in Solid Organ Transplant Recipients.

medRxiv : the preprint server for health sciences·2025
Same author

[Paraneoplastic limbic encephalitis - an important differential diagnosis in cases of unclear encephalopathy].

Praxis·2025
Same author

Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage.

JCI insight·2025
Same author

Perinephric myxoid pseudotumor of fat - histopathological and molecular characterization of 3 cases after renal transplantation.

Diagnostic pathology·2025
Same author

[Albumin-corrected calcium].

Praxis·2025
Same journal

Beyond galactose deficiency: redefining pathogenic IgA in IgA nephropathy.

Kidney international·2026
Same journal

KDIGO Life Cycle of Guideline Development Series Part 6: Bridging the Gap between Guidelines and Clinical Practice: The KDIGO Approach to Global Implementation and Education in Nephrology.

Kidney international·2026
Same journal

KDIGO Life Cycle of Guideline Development Series Part 5: Guideline updates and a living model for the future.

Kidney international·2026
Same journal

Crystal-storing histiocytosis causing severe acute kidney injury.

Kidney international·2026
Same journal

Peritoneal dialysis in a patient with extensive burn scarring.

Kidney international·2026
Same journal

COPA syndrome unmasked by anti-neutrophil cytoplasmic antibody-positive immune-complex nephritis.

Kidney international·2026
See all related articles

Related Experiment Video

Updated: May 27, 2026

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography
09:23

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography

Published on: September 22, 2023

Predicting an allograft's fate.

Thomas Fehr, Clemens D Cohen

    Kidney International
    |December 1, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Researchers identified gene expression patterns that predict chronic damage in kidney transplants, even before visible changes occur. These

    More Related Videos

    In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
    18:48

    In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

    Published on: August 12, 2017

    Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
    07:05

    Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis

    Published on: May 17, 2015

    Related Experiment Videos

    Last Updated: May 27, 2026

    Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography
    09:23

    Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography

    Published on: September 22, 2023

    In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
    18:48

    In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

    Published on: August 12, 2017

    Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
    07:05

    Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis

    Published on: May 17, 2015

    Area of Science:

    • Nephrology
    • Immunology
    • Genomics

    Background:

    • Kidney allografts often experience progressive functional decline.
    • Chronic damage can occur even in transplants without obvious histological abnormalities.

    Purpose of the Study:

    • To identify transcriptional markers predicting rapid chronic damage in kidney allografts.
    • To understand the molecular processes underlying chronic allograft nephropathy.

    Main Methods:

    • Transcriptomic analysis of renal allografts.
    • Correlation of gene expression profiles with long-term graft function and damage.

    Main Results:

    • Identified specific gene expression patterns associated with rapid chronic damage.
    • These patterns were detectable even in histologically unremarkable allografts.
    • The identified processes resemble those in acute rejection.

    Conclusions:

    • Transcriptomic profiling can predict sub-morphological chronic damage in kidney allografts.
    • Early molecular changes mirror acute rejection processes.
    • This approach may improve understanding and management of chronic allograft failure.