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Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...

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Related Experiment Video

Updated: May 27, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
09:32

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

Published on: February 23, 2020

Cardiovascular predictors for long-term mortality after EVAR for AAA.

Tomas Ohrlander1, Magnus Dencker, Nuno V Dias

  • 1Eksjö County Hospital, Eksjö, Sweden.

Vascular Medicine (London, England)
|December 1, 2011
PubMed
Summary

Cardiovascular predictors like myocardial ischemia on electrocardiogram (ECG) and anemia are linked to increased long-term mortality after endovascular aneurysm repair (EVAR). These findings are crucial for preoperative patient assessment.

Related Experiment Videos

Last Updated: May 27, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
09:32

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

Published on: February 23, 2020

Area of Science:

  • Cardiovascular Medicine
  • Vascular Surgery
  • Medical Statistics

Background:

  • Endovascular aneurysm repair (EVAR) is a standard treatment for infrarenal abdominal aortic aneurysms (AAA).
  • Long-term mortality after EVAR is significant, with vascular diseases being a major cause.
  • Identifying predictors of long-term mortality is essential for improving patient outcomes.

Purpose of the Study:

  • To assess cardiovascular predictors of all-cause long-term mortality in patients undergoing EVAR for AAA.
  • To identify independent risk factors for mortality following EVAR.
  • To inform preoperative medical evaluation for EVAR patients.

Main Methods:

  • Prospective and retrospective data collection on 304 patients treated with EVAR between 1998 and 2006.
  • Assessment of medication, electrocardiographic (ECG), and echocardiographic variables.
  • Survival analysis using Cox regression to identify independent predictors of long-term mortality up to December 2010.

Main Results:

  • Overall mortality was 54.3% after a median follow-up of 68 months.
  • Myocardial ischemia on ECG (HR 1.6) and anemia (HR 1.5) were independent predictors of long-term mortality.
  • Low ejection fraction, absence of statins, and use of diuretics or digitalis were associated with increased mortality in univariate analysis.

Conclusions:

  • Myocardial ischemia on ECG and anemia are independently associated with increased long-term mortality after EVAR.
  • These factors are critical for preoperative assessment in patients undergoing EVAR for AAA.
  • Further research into managing these predictors may improve EVAR outcomes.