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Updated: May 27, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
Published on: February 20, 2021
Radiation dose to neonates undergoing X-ray imaging in special care baby units in Iran
Reza Faghihi1, Simin Mehdizadeh, Sedigheh Sina
1Radiation Research Center, School of Mechanical Engineering, Shiraz University, Mollasadra Street, Shiraz, Iran. faghihir@shirazu.ac.ir
Insights
Neonatal radiographic imaging dose estimation is crucial due to infant radiosensitivity. This study compared direct, indirect, and Monte Carlo methods for entrance skin dose (ESD) and childhood cancer risk, finding comparable results across methods.
Area of Science:
- Medical Physics
- Pediatric Radiology
- Radiation Dosimetry
Background:
- Radiographic imaging is vital for diagnosing neonatal intensive care unit (NICU) diseases.
- Accurate dose estimation is critical for neonates due to their increased radiosensitivity and longer life expectancy.
Purpose of the Study:
- To estimate radiation dose metrics including entrance skin dose (ESD), dose area product (DAP), and effective dose in neonates undergoing radiography.
- To assess the risk of childhood cancer associated with these radiographic procedures.
- To compare the accuracy of direct (TLD), indirect (tube output), and Monte Carlo (MC) methods for dose estimation.
Main Methods:
- Direct measurement of ESD using thermoluminescence dosimetry (TLD-100) chips in 50 neonates (primarily premature).
- Indirect estimation of ESD based on tube output measurements for various imaging techniques.
- Simulation of imaging environments and patient components using MCNP4C code for MC-based ESD estimation.
- Calculation of DAP, energy imparted (EI), whole-body dose, effective dose, and childhood cancer risk using assessed ESD values.
Main Results:
- Mean ESD per radiograph: 56.6±4.1 μGy (direct), 50.1±3.1 μGy (indirect), and 54.5±3.3 μGy (MC).
- The estimated mean risk of childhood cancer ranged from 4.21×10⁻⁷ to 2.72×10⁻⁶.
Conclusions:
- All three methods (direct, indirect, MC) provide comparable estimations for neonatal radiographic doses.
- The findings underscore the importance of meticulous dose assessment in pediatric radiography to minimize long-term risks like childhood cancer.
Abstract:
Radiographic imaging has a significant role in the timely diagnosis of the diseases of neonates in intensive care units. The estimation of the dose received by the infants undergoing radiographic examination is of great importance, due to greater more radiosensitivity and longer life expectancy of the neonates and premature babies. In this study, the values of entrance skin dose (ESD), dose area products (DAPs), energy imparted (EI), whole-body dose, effective dose and risk of childhood cancer were estimated using three methods including direct method [using thermoluminescence dosimetry (TLD) chips], indirect method (using tube output) and Monte Carlo (MC) method (using MCNP4C code). In the first step, the ESD of the neonates was directly measured using TLD-100 chips. Fifty neonates, mostly premature, with different weights and gestational ages in five hospitals mostly suffering from respiratory distress syndrome and pneumonia were involved in this study. In the second step, the values of ESD to neonates were indirectly obtained from the tube output in different imaging techniques. The imaging room, incubator, neonates and other components were then simulated in order to obtain the ESD values using the MCNP4C code. Finally, the values of ESD assessed by the three methods were used for calculation of DAP, EI, whole-body dose, effective dose and risk of childhood cancer. The results indicate that the mean ESD per radiograph estimated by the direct, indirect and MC methods are 56.6±4.1, 50.1±3.1 and 54.5±3.3 μGy, respectively. The mean risk of childhood cancer estimated in this study varied between 4.21×10(-7) and 2.72×10(-6).
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