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Revisiting issues, drawbacks and opportunities with observational studies in comparative effectiveness research

Demissie Alemayehu1, Joseph C Cappelleri

  • 1Specialty Care Biostatistics, Pfizer Inc., New York, NY, USA.

Journal of Evaluation in Clinical Practice
|December 2, 2011
PubMed
Summary

Observational studies from secondary data sources are crucial for healthcare decisions but have limitations. Improving causal inference and careful interpretation are essential for reliable results.

Keywords:
biascomparative effectiveness researchconfoundersobservational studiespharmacoepidemiologysecondary sources of data

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