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Updated: May 27, 2026

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
The breast cancer genome--a key for better oncology
Hans Kristian Moen Vollan1, Carlos Caldas
1Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute, Cambridge, UK. carlos.caldas@cancer.org.uk.
Abstract:
Molecular classification has added important knowledge to breast cancer biology, but has yet to be implemented as a clinical standard. Full sequencing of breast cancer genomes could potentially refine classification and give a more complete picture of the mutational profile of cancer and thus aid therapy decisions. Future treatment guidelines must be based on the knowledge derived from histopathological sub-classification of tumors, but with added information from genomic signatures when properly clinically validated. The objective of this article is to give some background on molecular classification, the potential of next generation sequencing, and to outline how this information could be implemented in the clinic.
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