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Inappropriate nonsteroidal anti-inflammatory drug use: prevalence and predictors.
Stacey H Kovac1, Thomas K Houston, Morris Weinberger
1Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, North Carolina, USA.
Journal of Patient Safety
|December 2, 2011
Summary
Inappropriate nonsteroidal anti-inflammatory drug (NSAID) use is common, affecting 32% of patients. Minority status and lower income predict this risky behavior, which is linked to more gastrointestinal symptoms and pain.
Area of Science:
- Pharmacology and Therapeutics
- Patient Safety
- Public Health
Background:
- Inappropriate nonsteroidal anti-inflammatory drug (NSAID) use, including polypharmacy or exceeding dosage, poses risks.
- Prevalence and predictors of inappropriate NSAID use remain largely unknown.
- Understanding these factors is crucial for mitigating potential harm.
Purpose of the Study:
- To determine the prevalence of inappropriate NSAID use.
- To identify patient characteristics associated with inappropriate NSAID use.
Main Methods:
- Pharmacy records identified 6877 patients with frequent NSAID prescriptions.
- A survey was mailed to 2535 randomly selected patients to assess NSAID use, symptoms, and pain.
- Inappropriate use was defined as taking multiple NSAIDs or exceeding dosage recommendations.
Main Results:
- Of 1250 patients reporting NSAID use, 32% exhibited inappropriate use.
- Factors predicting inappropriate use included minority status and income ≤$20,000.
- Inappropriate NSAID use correlated with increased gastrointestinal symptoms and pain levels.
Conclusions:
- Inappropriate NSAID use is a prevalent issue.
- Healthcare providers should counsel all patients on safe NSAID practices.
- Particular attention should be given to patients experiencing gastrointestinal issues or pain.
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