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Updated: May 27, 2026
A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
PGAP: pan-genomes analysis pipeline
Yongbing Zhao1, Jiayan Wu, Junhui Yang
1CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, People's Republic of China.
Summary:
With the rapid development of DNA sequencing technology, increasing bacteria genome data enable the biologists to dig the evolutionary and genetic information of prokaryotic species from pan-genome sight. Therefore, the high-efficiency pipelines for pan-genome analysis are mostly needed. We have developed a new pan-genome analysis pipeline (PGAP), which can perform five analytic functions with only one command, including cluster analysis of functional genes, pan-genome profile analysis, genetic variation analysis of functional genes, species evolution analysis and function enrichment analysis of gene clusters. PGAP's performance has been evaluated on 11 Streptococcus pyogenes strains.
Availability:
PGAP is developed with Perl script on the Linux Platform and the package is freely available from http://pgap.sf.net.
Contact:
junyu@big.ac.cn; xiaojingfa@big.ac.cn
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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