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Updated: May 27, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
[Combined retinal artery and vein occlusions associated with interferon beta therapy]
T Jenisch1, T Dietrich-Ntoukas, A B Renner
1Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Joseph-Str.-Allee 11, 93053, Regensburg, Deutschland. T.Jenisch@web.de
Abstract:
Interferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.
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