Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypoglycemia and Glucagon

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...

Hypoglycemia

Hypoglycemia

Hypoglycemia is a blood glucose level below 70 mg/dL. It commonly occurs in individuals using insulin or insulin-secreting drugs, but may also arise in non-diabetic conditions. People with type 1 diabetes are at the highest risk because they depend on exogenous insulin. People with type 2 diabetes are also at risk, especially when treated with insulin or medications such as sulfonylureas, which increase insulin release regardless of blood glucose levels. It develops when insulin levels exceed...

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Hyperglycemia

Hyperglycemia

Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...

Oral Hypoglycemic Agents: Glinides

Oral Hypoglycemic Agents: Glinides

Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively manages...

Diabetes Mellitus: Overview and Type I Subtype

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The older person with diabetes: considerations for care.

British journal of community nursing·2019

Same author

Why supporting patients to self-manage their diabetes in the community is important.

British journal of community nursing·2017

Same author

The Nurse's Role in Health Literacy of Patients With Cancer.

Clinical journal of oncology nursing·2016

Same author

The impact of a diabetes local enhanced service on quality outcome framework diabetes outcomes.

PloS one·2013

Same author

Preventing type 2 diabetes: a role for every practitioner.

Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association·2012

Same author

Reducing the risk of complications associated with diabetes.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2009

Search research articles

Related Experiment Video

Updated: May 27, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

How to manage hypoglycaemia.

¹Birmingham Community Healthcare Trust.

|December 3, 2011

Summary

This summary is machine-generated.

Hypoglycaemia, a common side-effect of diabetes treatments, impacts quality of life and can be fatal. Nurses play a vital role in identifying, treating, and supporting patients at risk of this condition.

More Related Videos

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice

Published on: January 26, 2024

Related Experiment Videos

Last Updated: May 27, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice

Published on: January 26, 2024

Area of Science:

Endocrinology
Diabetes Management
Nursing Care

Background:

Hypoglycaemia is a frequent adverse effect of insulin and certain oral hypoglycaemic medications.
This condition significantly impairs the quality of life for individuals with diabetes.
Severe hypoglycaemia poses a risk to achieving optimal blood glucose control and can be life-threatening.

Purpose of the Study:

To define hypoglycaemia and elucidate its common causes.
To outline methods for identifying and treating hypoglycaemic events.
To describe the role of nurses in supporting patients susceptible to hypoglycaemia.

Main Methods:

Literature review on hypoglycaemia in diabetes management.
Clinical guidelines analysis for identification and treatment protocols.
Nursing interventions for patient support and risk mitigation.

Main Results:

Hypoglycaemia stems from insulin therapy and insulin secretagogues.
Early identification and prompt treatment are crucial for managing blood glucose levels.
Nurses are essential in educating patients and preventing complications.

Conclusions:

Understanding hypoglycaemia is critical for safe diabetes care.
Effective management strategies and nursing support improve patient outcomes.
Preventing and treating hypoglycaemia enhances quality of life and reduces diabetes-related risks.