Related Experiment Video
Updated: May 27, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
Published on: August 18, 2023
Opioid-induced constipation in children's palliative care.
Grace Stewart1, Patricia McNeilly
1Northern Ireland Children's Hospice. gstewart@nihospice.org
Managing opioid-induced constipation in children receiving palliative care is crucial. This article explores novel approaches beyond conventional laxatives to alleviate this common side effect and reduce distress for patients and families.
Area of Science:
- Pediatric Palliative Care
- Pain Management
- Gastroenterology
Background:
- Opioid analgesics are essential for managing pain in children at the end of life.
- Opioid-induced constipation (OIC) is a prevalent and distressing side effect in this population.
- Current management strategies, including laxatives, have limitations and potential side effects.
Purpose of the Study:
- To review current understanding of OIC in pediatric palliative care.
- To explore emerging and novel management strategies for OIC in children.
- To highlight the need for evidence-based approaches in this specialized area.
Main Methods:
- Literature review of OIC management in pediatric palliative care.
- Exploration of conventional and novel pharmacological interventions.
- Discussion of assessment tools for OIC risk and severity.
Main Results:
- Conventional laxatives are commonly used but can cause further distress.
- Novel approaches to OIC management are emerging but have limited documented use in children.
- Accurate assessment is key to effective OIC management.
Conclusions:
- Effective management of OIC is vital for children's comfort and quality of life.
- There is a need for further research into novel OIC treatments for pediatric palliative care.
- Integrating new strategies can improve care for children experiencing OIC.
Related Concept Videos
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
Drugs for Treatment of Constipation-Predominant IBS
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Drugs Affecting GI Tract Motility: Other Laxatives
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Opioid Analgesics: Morphine and Other Natural Cogeners
Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This makes...