Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early changes in cognitive function following bariatric surgery: evidence for rapid improvement or practice effects?

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same author

Food Noise: Current Knowledge and Future Research Directions.

Obesity (Silver Spring, Md.)·2026
Same author

Preoperative Weight Trends in Adolescents Undergoing Metabolic and Bariatric Surgery.

Obesity (Silver Spring, Md.)·2026
Same author

Genome-wide association studies of binge eating behaviour and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes.

medRxiv : the preprint server for health sciences·2025
Same author

The relationship between physical activity, sedentary time, and cognitive function following bariatric surgery.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2025
Same author

Early changes in the gut microbiota are associated with weight outcomes over 2 years following metabolic and bariatric surgery.

Obesity (Silver Spring, Md.)·2024
Same journal

Predictors of 1-year weight maintenance after intragastric balloon removal: a real-world cohort study of 478 patients.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same journal

Late hiatal hernia after Roux-en-Y gastric bypass: a systematic review.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same journal

Comment on: The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program's role in the evolution of quality in metabolic and bariatric surgery.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same journal

Paired editorial: Endoscopic septotomy with argon plasma coagulation (ES-APC) for the management of refractory postbariatric surgery fistulas and leaks (with video): results from a tertiary referral center.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same journal

Paired editorial: "The impact of obesity onset and duration on outcomes after metabolic bariatric surgery: an international multicenter cohort study".

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same journal

Metabolic and bariatric surgery and risk of cardiac arrhythmias and mortality in severe obesity: a multicenter real-world propensity-matched study.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
See all related articles

Related Experiment Video

Updated: May 27, 2026

Roux-en-Y Gastric Bypass Operation in Rats
07:37

Roux-en-Y Gastric Bypass Operation in Rats

Published on: June 11, 2012

Cognitive function predicts weight loss after bariatric surgery.

Mary Beth Spitznagel1, Sarah Garcia, Lindsay A Miller

  • 1Kent State University, Kent, OH 44195 , USA. mspitzna@kent.edu

Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery
|December 3, 2011
PubMed
Summary
This summary is machine-generated.

Cognitive function, including attention and memory, at baseline predicts successful weight loss after bariatric surgery. Better cognitive performance correlates with greater excess weight loss (EWL) and lower body mass index (BMI) one year post-operation.

More Related Videos

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
10:05

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

Published on: March 20, 2017

Related Experiment Videos

Last Updated: May 27, 2026

Roux-en-Y Gastric Bypass Operation in Rats
07:37

Roux-en-Y Gastric Bypass Operation in Rats

Published on: June 11, 2012

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
10:05

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

Published on: March 20, 2017

Area of Science:

  • Neuroscience
  • Bariatric Surgery Outcomes
  • Cognitive Function Assessment

Background:

  • Cognitive impairment affects some patients undergoing bariatric surgery, potentially reducing adherence and weight loss.
  • Baseline cognitive function, specifically executive function/attention and verbal memory, was hypothesized to negatively predict weight loss outcomes.
  • This study prospectively investigated the independent contribution of cognitive function to weight loss after bariatric surgery.

Purpose of the Study:

  • To determine if baseline cognitive function independently predicts weight loss after bariatric surgery.
  • To examine the relationship between executive function, attention, verbal memory, and percentage of excess weight loss (%EWL) and body mass index (BMI) at 12 months post-surgery.

Main Methods:

  • 84 bariatric surgery patients from the Longitudinal Assessment of Bariatric Surgery project completed baseline cognitive evaluations.
  • Body mass index (BMI) and percentage of excess weight loss (%EWL) were measured at 12-week and 12-month postoperative follow-ups.
  • Statistical analyses accounted for demographic and medical variables to assess the predictive value of cognitive tests.

Main Results:

  • Impairments were most notable in verbal recall/recognition and perseverative errors.
  • Baseline attention/executive function and memory significantly predicted 12-month BMI and %EWL.
  • Cognitive function did not predict outcomes at the 12-week follow-up.

Conclusions:

  • Baseline cognitive abilities are significant predictors of greater %EWL and lower BMI at 12 months post-bariatric surgery.
  • Further research is required to understand cognition's role in adherence and its mediating effect on weight loss.
  • Cognitive assessment may inform personalized post-bariatric surgery care plans.