Related Experiment Video
Updated: May 27, 2026

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
Published on: January 8, 2020
Lacrimal gland ductulitis caused by probable Actinomyces infection
Graham Hay-Smith1, Geoffrey E Rose
1Moorfields Eye Hospital, London, United Kingdom.
Objective:
To describe the clinical characteristics and management of a group of patients who had chronic mucopurulent conjunctivitis that was probably due to Actinomyces infection of the lacrimal gland ductules.
Design:
A retrospective, interventional case series.
Participants:
Seven patients (2 male; 29%) between 34 and 52 years of age (mean, 48.7 years; median, 49 years) who presented to the lacrimal clinic.
Intervention:
Surgical excision of the infective focus (6 cases) or fenestration and expression of infective debris (1 case) from the affected lacrimal gland ductule--typically the most inferolateral of the ductules.
Main Outcome Measures:
The clinical features of this previously unrecognized cause of chronic conjunctivitis and its response to treatment.
Results:
All cases settled rapidly after surgery. There was often a major delay in diagnosis, with the patients having symptoms for between 2 and 42 months before referral (mean, 13.3 months; median, 9 months); 5 patients received prolonged or ineffectual topical medical therapy before referral.
Conclusions:
Infective lacrimal gland ductulitis, commonly from Actinomyces infection, should be considered in patients with unexplained chronic mucopurulent conjunctivitis; the condition settles rapidly with surgery.
Financial Disclosure(S):
Proprietary or commercial disclosure may be found after the references.
Related Concept Videos
Diphtheria
Microbiome of the Eye
Bacterial Phylum Actinobacteria
Angle Closure Glaucoma: Treatment
Accessory Structures of the Eye
Staphylococcal Skin Infections

