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Updated: May 27, 2026

An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
Published on: December 25, 2021
Revised requirements for radiation emergency bioassay techniques for the public and first responders
1Radiation Protection Bureau, Health Canada, Ottawa, ON, Canada K1A 1C1. li.chunsheng@hc-sc.gc.ca
Abstract:
This technical note reports the required sensitivities for bioassay techniques derived from a 0.1 Sv effective dose incurred in the first year following an emergency (recommended by ICRP) and those derived from a 0.25 Sv committed effective dose (recommended by NCRP) as dose thresholds for possible medical attention. During a large-scale radiological or nuclear emergency, the dose threshold chosen for medical attention may be raised, as available resources may be insufficient for conducting a sensitive contamination assessment and medical treatment of a large population exposed to radioactive contamination.
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