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Cricoid-based extramedullary plasmocytoma.

Barbara Pichi1, Valentina Terenzi, Renato Covello

  • 1Department of Otolaryngology Head and Neck Surgery, National Cancer Institute Regina Elena, Rome, Italy. barbapichi@libero.it

The Journal of Craniofacial Surgery
|December 3, 2011
PubMed
Summary
This summary is machine-generated.

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Extramedullary plasmocytomas are rare head and neck tumors. One case report details a cricoid and vocal cord plasmacytoma progressing to multiple myeloma within a year.

Area of Science:

  • Oncology
  • Pathology
  • Head and Neck Surgery

Background:

  • Extramedullary plasmacytomas (EMPs) are rare plasma cell neoplasms.
  • They represent approximately 1% of malignancies in the head and neck.
  • A significant proportion of EMPs can progress to multiple myeloma (MM).

Observation:

  • EMPs commonly affect the larynx, with specific sites including the epiglottis, ventricle, true vocal cord, false vocal cord, aryepiglottic fold, arytenoids, and subglottis.
  • This report focuses on a rare case of EMP involving the cricoid cartilage, left cricoarytenoid joint, and the ipsilateral vocal process.
  • The patient presented with symptoms related to laryngeal involvement.

Findings:

  • The described laryngeal EMP demonstrated aggressive behavior.

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  • The tumor progressed to multiple myeloma (MM) within one year following initial treatment.
  • This progression highlights the potential for localized disease to transform into systemic malignancy.

    • Implications:

    • Early detection and vigilant monitoring of laryngeal EMPs are crucial.
    • Understanding the risk factors and progression patterns of EMPs is essential for timely intervention.
    • This case underscores the importance of considering systemic disease in patients with apparently localized head and neck plasma cell tumors.