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Updated: May 27, 2026
06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Intraosseous mandibular venous malformation
Emmanouil Vardas1, Emmanouil Stavrou, Minas Leventis
1Departments of Hospital Dentistry, Faculty of Dentistry, University of Athens, Athens, Greece.
The Journal of Craniofacial Surgery
|December 3, 2011
Summary
Intraosseous venous malformations, rare bone tumors, can occur in the jaw. This case study details a successful surgical removal of a mandibular lesion, with no recurrence observed.
Area of Science:
- Oral and Maxillofacial Surgery
- Vascular Malformations
- Oncology
Background:
- Intraosseous venous malformations (IVMs) are uncommon benign vascular tumors of bone, representing 0.5-1% of all bone tumors.
- Facial skeleton involvement is rare, with the mandible and maxilla being the most common sites.
- Previous history of keratocystic odontogenic tumor (KCOT) is noted in this patient.
Observation:
- A 52-year-old male presented with an asymptomatic bony lesion in the mandible.
- The lesion was surgically excised for definitive diagnosis and treatment.
- Histopathological examination confirmed the diagnosis of an intraosseous venous malformation.
Findings:
- Surgical excision was the chosen treatment modality for the mandibular IVM.
- Postoperative follow-up at 12 months showed no signs of recurrence.
- The patient's history of KCOT did not complicate the management of the IVM.
Implications:
- This case highlights the importance of accurate diagnosis and surgical management of rare intraosseous vascular lesions.
- Complete surgical excision appears to be an effective treatment for mandibular IVMs, leading to favorable outcomes.
- Further research into the potential association between KCOT and IVM development may be warranted.
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