Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Geographic Access to Pediatric Retina Specialists in the United States.

Ophthalmic surgery, lasers & imaging retina·2026
Same authorSame journal

Traumatic macular hole: observe, operate, or other options.

Current opinion in ophthalmology·2026
Same author

Multimodal Imaging of Neurofibromatosis Type 1 Choroidopathy.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Two-Hit Mechanism of a Massive Retinal Pigment Epithelium Tear in Hypertensive Choroidopathy Superimposed on Chronic Central Serous Chorioretinopathy.

Journal of vitreoretinal diseases·2026
Same author

Readability of Retina Patient Education Materials Generated With a Large Language Model.

Journal of vitreoretinal diseases·2026
Same author

Clinical Outcomes of Ocular Toxoplasmosis-Associated Rhegmatogenous and Tractional Retinal Detachment.

Journal of vitreoretinal diseases·2026

Related Experiment Video

Updated: May 27, 2026

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Pseudophakic cystoid macular edema.

Yoshihiro Yonekawa1, Ivana K Kim

  • 1Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

Current Opinion in Ophthalmology
|December 3, 2011
PubMed
Summary
This summary is machine-generated.

Pseudophakic cystoid macular edema (PCME) incidence decreases with modern cataract surgery. Current treatments for chronic PCME are challenging, with investigational therapies showing promise but lacking robust clinical trial data.

More Related Videos

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Related Experiment Videos

Last Updated: May 27, 2026

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Cataract Surgery Complications

Background:

  • Pseudophakic cystoid macular edema (PCME) is a significant cause of vision loss post-cataract surgery.
  • Understanding PCME epidemiology, risk factors, and diagnostic methods is crucial for patient care.

Purpose of the Study:

  • To systematically review the epidemiology, risk factors, diagnosis, and treatment of PCME.
  • To highlight recent advancements in PCME management over the past 1-2 years.

Main Methods:

  • Systematic literature review focusing on recent studies (1-2 years).
  • Analysis of diagnostic modalities including optical coherence tomography (OCT), biomicroscopy, and fluorescein angiography.
  • Evaluation of current and investigational therapeutic strategies.

Main Results:

  • PCME incidence has decreased due to improved surgical techniques.
  • OCT is a key diagnostic tool, complementing traditional methods.
  • Prophylaxis with NSAIDs lacks proven long-term efficacy; chronic PCME remains difficult to treat.
  • Investigational treatments include intravitreal corticosteroids and anti-VEGF agents; surgical options are understudied.

Conclusions:

  • There is a notable lack of high-quality randomized clinical trials to guide PCME treatment decisions.
  • Further research is needed to establish evidence-based protocols for managing chronic and refractory PCME.