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Gastric motility functional study based on electrical bioimpedance measurements and simultaneous electrogastrography
Zhang-Yong Li1, Chao-Shi Ren, Shu Zhao
1College of Bioinformation, Chongqing University of Posts and Telecommunications, China.
Journal of Zhejiang University. Science. B
|December 3, 2011
Summary
A new noninvasive method combining bioimpedance and electrogastrography (EGG) assesses gastric motility. This study found functional dyspepsia (FD) patients exhibit poor gastric motility, which improved after three weeks of treatment.
Area of Science:
- Gastroenterology
- Medical Devices
- Physiology
Background:
- Gastric motility research has lagged behind other areas of gastric study.
- A noninvasive method is needed to simultaneously assess electrical and mechanical gastric activity.
Purpose of the Study:
- To develop and validate a noninvasive method for studying gastric motility.
- To compare gastric motility in healthy subjects, functional dyspepsia (FD), and gastritis patients.
- To evaluate treatment effects on gastric motility in FD and gastritis.
Main Methods:
- Developed impedance gastric motility (IGM) measurements.
- Simultaneously recorded bioimpedance and electrogastrography (EGG).
- Conducted preliminary clinical studies on healthy, FD, and gastritis subjects.
Main Results:
- FD subjects showed significantly poorer gastric motility compared to healthy controls.
- Gastric motility in FD subjects improved after three weeks of treatment, while EGG normalized after one week.
- Gastritis subjects exhibited significant differences in IGM parameters compared to healthy subjects.
Conclusions:
- The combined bioimpedance and EGG method shows promise for assessing gastric motility.
- The developed method can differentiate between healthy, FD, and gastritis patients.
- Treatment response in FD and gastritis can be monitored using this novel technique.
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