Related Experiment Video
Updated: May 27, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Optimal management of shivering during therapeutic hypothermia after cardiac arrest
Angela Logan1, Prasama Sangkachand, Marjorie Funk
1Yale School of Nursing, Yale University, New Haven, Connecticut 06536-0740, USA. angela.logan@yale.edu
Abstract:
Both pharmacological and nonpharmacological methods are used to control shivering in therapeutic hypothermia. An evidence-based protocol based on the most current research has been developed for the management of shivering during therapeutic hypothermia. Meperidine is the drug of choice and provides the greatest reduction in the shivering threshold. Other effective pharmacological agents recommended for reducing the threshold include dexmedetomidine, midazolam, fentanyl, and magnesium sulfate. In addition, skin counterwarming techniques, such as use of an air-circulating blanket, are effective nonpharmacological methods for reducing shivering when used in conjunction with medication. As a last resort, neuromuscular blocking agents are considered appropriate therapy for management of refractory shivering.
More Related Videos
Related Concept Videos
Decreased Body Temperature
Cardiopulmonary Resuscitation IV: Pharmacological Management
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Thermoregulation
Increased Body Temperature
Body Temperature

