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Related Experiment Video

Updated: May 27, 2026

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
09:46

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Published on: September 14, 2009

Stent longitudinal integrity bench insights into a clinical problem.

John A Ormiston1, Bruce Webber, Mark W I Webster

  • 1Mercy Angiography, Mercy Hospital, Auckland, New Zealand.

JACC. Cardiovascular Interventions
|December 6, 2011
PubMed
Summary

Coronary stents with fewer connectors have less longitudinal strength, increasing risks of distortion and adverse events. Optimizing connector number can improve stent integrity and patient outcomes.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Materials Science

Background:

  • Coronary stents rely on hoops and connectors for radial support and longitudinal integrity.
  • Stent design (strut, connector number/configuration) influences flexibility versus strength.
  • Longitudinal distortion can lead to malapposition, obstruction, and adverse clinical events like restenosis or thrombosis.

Purpose of the Study:

  • To assess the longitudinal strength of contemporary coronary stents using standardized testing.
  • To correlate stent design features, specifically connector number, with longitudinal integrity.
  • To inform clinical stent selection, deployment techniques, and future stent design.

Main Methods:

  • Bench-top compression and elongation testing of 7 contemporary stents using an Instron universal testing machine.

Related Experiment Videos

Last Updated: May 27, 2026

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
09:46

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Published on: September 14, 2009

  • Microcomputed tomography imaging of stents deployed in a silicone phantom to analyze distortion effects.
  • Measurement of forces required for stent compression and elongation.

    • Main Results:

    • Stents with 2 connectors demonstrated significantly lower resistance to compression and elongation compared to designs with more connectors.
    • The 6-connector Cypher Select required the highest force for elongation.
    • Fewer connectors correlate with reduced longitudinal strength.

    Conclusions:

    • Stents with fewer connectors (e.g., 2) exhibit less longitudinal strength, making them more susceptible to shortening or elongation.
    • This distortion can be clinically misinterpreted and increase risks for adverse events.
    • Increasing connector number (e.g., to 3) may enhance longitudinal integrity, potentially impacting flexibility.