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Updated: May 27, 2026

Preparation of Food Samples Using Homogenization and Microwave-Assisted Wet Acid Digestion for Multi-Element Determination with ICP-MS
Published on: December 22, 2023
Critical overview of selected contemporary sample preparation techniques
1Department of Instrumental Analysis and Environmental Chemistry, Institute of Organic Chemistry, CSIC, Juan de Cierva 3, 28006 Madrid, Spain. l.ramos@iqog.csic.es
This review highlights recent advancements in analytical sample preparation, focusing on simplifying tedious, manual methods. New techniques offer faster, cost-effective, and greener solutions for analyzing real-world samples, especially for minor organic components.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Conventional sample preparation methods are often manual, time-consuming, and prone to errors.
- There is a growing demand for analytical methods that are faster, more economical, and environmentally friendly.
Purpose of the Study:
- To provide an overview of recent developments and successful approaches in analytical sample preparation.
- To discuss the state-of-the-art in sample preparation techniques for various application areas.
- To evaluate the potential and limitations of new sample treatment strategies.
Main Methods:
- Review of recent literature on sample preparation techniques.
- Selection of examples from diverse application areas.
- Focus on techniques practical for real-life sample analysis, particularly for minor organic compounds.
Main Results:
- Identification of key innovations in sample preparation.
- Demonstration of practical applicability of advanced techniques in real-world analyses.
- Emphasis on methods suitable for determining trace organic analytes.
Conclusions:
- Recent developments offer significant improvements in simplifying sample preparation.
- The potential for integrated and automated analytical processes is increasing.
- Further research is needed to address remaining limitations in sample treatment.
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