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A practical approach to the painful bladder syndrome
1Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
The Journal of Reproductive Medicine
|August 1, 1990
Summary
Painful bladder syndrome (PBS) treatment involving bladder pillar block, distention, and DMSO instillation provided significant symptomatic relief in 80% of patients. This therapy also increased bladder capacity, demonstrating its effectiveness for PBS management.
Area of Science:
- Urology
- Gynecology
Background:
- Painful bladder syndrome (PBS) is a chronic condition causing bladder pain, urgency, and frequency.
- It can lead to bladder fibrosis, contracture, and reduced capacity.
- Symptoms include pelvic pain, lower abdominal pain, and nocturia.
Purpose of the Study:
- To evaluate the efficacy of a treatment regimen for painful bladder syndrome (PBS).
- To assess symptomatic relief and changes in bladder capacity in women with PBS.
Main Methods:
- Retrospective analysis of 21 women diagnosed with PBS.
- Weekly treatment included bladder pillar block, bladder distention, and dimethyl sulfoxide (DMSO) instillation.
- Data collected on symptom relief and bladder volume.
Main Results:
- 80% of patients experienced symptomatic relief.
- Maximum bladder volume significantly increased from 185 mL to 475 mL (P < .01).
- Treatment resulted in minimal side effects.
Conclusions:
- A combination therapy of bladder pillar block, distention, and DMSO instillation is effective for managing painful bladder syndrome.
- This treatment approach offers significant symptomatic improvement and functional bladder capacity enhancement.
- The therapeutic regimen is well-tolerated with minimal adverse events.