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Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates
Published on: March 7, 2014
Improvement of neuronal cell adhesiveness on parylene with oxygen plasma treatment
Takayuki Hoshino1, Itsuro Saito, Reo Kometani
1Graduate School of Bio-Application and System Engineering, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan.
Journal of Bioscience and Bioengineering
|December 6, 2011
Abstract:
We improved adhesiveness of a neuron-like cell, PC12, on a Parylene-C surface by O(2) plasma treatment which changes the surface from hydrophobic to hydrophilic. Neural cell adhesiveness on the plasma-treated Parylene-C was more than twenty times better compared to non-treated Parylene-C and it was close to that on a conventional polystyrene tissue-culture dish.
