Mean pulmonary arterial pressure after percutaneous mitral valvuloplasty predicts long-term adverse outcomes

Elisabete Jorge1, Rui Baptista, Henrique Faria

  • 1Cardiology Department, Coimbra Hospital and Medical School, Coimbra, Portugal. elisabetejorge@gmail.com

Abstract

Insights

Immediate post-percutaneous mitral valvuloplasty (PMV) mean pulmonary artery pressure (mPAP) predicts mitral re-intervention in mitral stenosis (MS) patients. Higher mPAP identifies individuals requiring closer follow-up after PMV.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Percutaneous mitral valvuloplasty (PMV) is a key treatment for mitral stenosis (MS).
  • Long-term outcomes and predictors of re-intervention after PMV require further characterization.
  • Existing studies often have limited follow-up durations.

Purpose of the Study:

  • To assess long-term outcomes in patients undergoing PMV for MS.
  • To identify independent predictors of mitral re-intervention and event-free survival post-PMV.
  • To inform patient selection and follow-up strategies.

Main Methods:

  • A cohort of 91 consecutive MS patients undergoing PMV was studied.
  • Median clinical follow-up was 99 months.
  • Endpoints included mitral re-intervention and a composite clinical events outcome.

Main Results:

  • Long-term event-free survival rates were observed over 9 years.
  • Mitral re-intervention-free survival rates were also tracked.
  • Higher post-PMV mean pulmonary artery pressure (mPAP) ≥25 mmHg was the sole predictor of mitral re-intervention and clinical events.

Conclusions:

  • Immediate post-PMV mPAP is a critical predictor of subsequent mitral re-intervention.
  • Elevated mPAP identifies patients at higher risk for adverse outcomes.
  • These findings support closer post-PMV monitoring for high-risk individuals.

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