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Updated: May 27, 2026
10:03
Transplantation of Induced Pluripotent Stem Cell-derived Mesoangioblast-like Myogenic Progenitors in Mouse Models of Muscle Regeneration
Published on: January 20, 2014
Prospects for translational regenerative medicine
Fa-Ming Chen1, Yi-Min Zhao, Yan Jin
1Department of Periodontology & Oral Medicine, School of Stomatology, Fourth Military Medical University, Xi'an 710032, Shaanxi, PR China. cfmsunhh@fmmu.edu.cn
Biotechnology Advances
|December 6, 2011
Summary
Translational medicine accelerates research from lab to patient care. Translational regenerative medicine faces challenges but offers future therapeutic potential through collaboration.
Area of Science:
- Biomedical research
- Regenerative medicine
- Clinical translation
Background:
- Translational medicine bridges basic science and clinical application for disease diagnosis, prevention, and treatment.
- The field has gained significant traction, guiding research towards patient-centered outcomes.
- Translational regenerative medicine, while promising, is nascent with unmet clinical needs.
Purpose of the Study:
- To review the progress and transformation of translational medicine over the last decade.
- To outline current challenges and opportunities in translational regenerative medicine.
- To emphasize the need for collaboration in developing effective regenerative therapies.
Main Methods:
- Literature review of translational medicine advancements.
- Analysis of progress in translational regenerative medicine, focusing on stem cell therapy and tissue engineering.
- Identification of obstacles and opportunities in clinical translation of regenerative approaches.
Main Results:
- Translational medicine has evolved significantly, influencing biomedical research paradigms.
- Translational regenerative medicine shows promise but faces hurdles in clinical application.
- Stem cell therapy and tissue engineering require further development for safe and effective tissue regeneration.
Conclusions:
- Multi-disciplinary and inter-disciplinary cooperation is crucial for advancing regenerative medicine.
- Accelerated development of regenerative therapies is needed for maximum patient benefit.
- Overcoming current challenges will pave the way for successful clinical translation of regenerative strategies.
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