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Published on: July 1, 2018
[Porcine eperythrozoonosis: from Eperythrozoon suis to Mycoplasma suis]
L E Hoelzle1, K M Felder, K Hoelzle
1Institut für Umwelt- und Tierhygiene, sowie Tiermedizin mit Tierklinik, Universität Hohenheim. ludwig.hoelzle@uni-hohenheim.de
Abstract:
Mycoplasma suis (formerly known as Eperythrozoon suis ) is the most prevalent agent causing haemolytic anaemia in swine. The disease is also known as porcine eperythrozoonosis. M.suis is a small, pleomorphic bacteria parasitizing porcine erythrocytes. To date, no in vitro cultivation system for M.suis has been established and, therefore, our knowledge about the characteristics of M.suis and the pathogenesis of porcine eperythrozoonosis is rather limited. M.suis can cause acute disease, but the major significance of M.suis infections lies in the fact that M.suis can establish chronic and persistent infections leading to a higher susceptibility to other infections, especially of the respiratory and digestive tracts. The present article summarizes the current knowledge of the pathogen, the clinical signs and pathogenesis, diagnostic as well as therapy and prophylaxis.
Insights
Mycoplasma suis, a bacteria causing swine haemolytic anaemia, can lead to chronic infections and increased susceptibility to other diseases. Current knowledge on its characteristics and disease pathogenesis remains limited due to a lack of in vitro cultivation systems.
Area of Science:
- Veterinary Microbiology
- Animal Pathology
Context:
- Mycoplasma suis (formerly Eperythrozoon suis) is the primary cause of swine haemolytic anaemia (porcine eperythrozoonosis).
- This small, pleomorphic bacterium infects porcine erythrocytes, but lacks an established in vitro cultivation system.
- Limited knowledge exists regarding M. suis characteristics and disease pathogenesis.
Purpose:
- To summarize current knowledge on Mycoplasma suis.
- To review clinical signs, pathogenesis, diagnostics, therapy, and prophylaxis of porcine eperythrozoonosis.
Summary:
- Mycoplasma suis causes acute haemolytic anaemia in swine.
- Chronic and persistent infections are significant, increasing susceptibility to secondary respiratory and digestive infections.
- The article consolidates information on the pathogen, disease, diagnosis, and management.
Impact:
- Highlights the limitations in understanding M. suis due to cultivation challenges.
- Emphasizes the economic and health impact of M. suis on swine populations.
- Provides a comprehensive overview for veterinarians and researchers in swine health.
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