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Derivation of Glial Restricted Precursors from E13 mice

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Vertebrate-specific glutaredoxin is essential for brain development.

Lars Bräutigam¹, Lena Dorothee Schütte, José Rodrigo Godoy

¹Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles Väg 2, 17177 Stockholm, Sweden.

Proceedings of the National Academy of Sciences of the United States of America

|December 6, 2011

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Glutaredoxin 2 is crucial for embryonic brain development, controlling neuron survival and axonal growth. Its redox regulation impacts key developmental pathways, highlighting its essential role in vertebrate development.

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