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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

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A parallel imaging approach to wide-field MR microscopy.

Mary Preston McDougall¹, Steven M Wright

¹Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USA. mpmcdougall@tamu.edu

Magnetic Resonance in Medicine

|December 6, 2011

Summary

This study introduces wide field-of-view magnetic resonance microscopy using parallel coils. This technique overcomes limitations of small field-of-view and low signal-to-noise ratio in magnetic resonance microscopy.

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Area of Science:

Biomedical Imaging
Magnetic Resonance Technology

Background:

Magnetic resonance microscopy (MRM) is historically limited by low signal-to-noise ratio (SNR) due to small voxel sizes.
Microcoils improve SNR but restrict the field-of-view, hindering MRM's use in histology and large-region imaging.

Purpose of the Study:

To develop a wide field-of-view magnetic resonance microscopy technique.
To overcome the field-of-view limitations of conventional MRM.

Main Methods:

Utilized a large array of narrow, parallel coils for magnetic resonance microscopy.
Employed parallel imaging techniques in conjunction with the coil array.

Main Results:

Achieved significant signal-to-noise ratio enhancement.
Demonstrated the ability to use parallel imaging techniques.
Reduced imaging time by over 100-fold compared to volume coils.
Maintained resolution and signal-to-noise ratio without compromise.

Conclusions:

The proposed wide field-of-view MRM technique effectively addresses SNR and field-of-view limitations.
This advancement enables MRM for broader histological and large-region imaging applications.
The method offers substantial speed improvements without sacrificing image quality.