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Published on: April 12, 2021
Elderly renal transplant recipients and renal dysfunction: a risk factor for hyperuricemia
Behzad Einollahi1, Hoda Einollahi, Zohreh Rostami
1Department of Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Summary
Posttransplant hyperuricemia is common in elderly kidney transplant recipients. This condition is linked to impaired kidney allograft function, highlighting a need for monitoring in this population.
Area of Science:
- Nephrology
- Transplantation
- Geriatric Medicine
Background:
- Limited data exist on posttransplant hyperuricemia in elderly renal transplant patients.
- Hyperuricemia is a condition characterized by elevated serum uric acid levels.
Purpose of the Study:
- To investigate the prevalence and risk factors of posttransplant hyperuricemia in elderly renal transplant recipients.
- To determine the correlation between hyperuricemia and renal allograft function in this demographic.
Main Methods:
- Retrospective study of 120 renal transplant patients aged 60 years or older.
- Hyperuricemia defined by specific serum uric acid thresholds for men and women, persisting over time.
- Moderate-to-severe hyperuricemia defined by a higher serum uric acid threshold.
Main Results:
- Prevalence of late posttransplant hyperuricemia was 37.5% (45 patients).
- Moderate-to-severe hyperuricemia occurred in 17.5% (21 patients).
- Hyperuricemia was more common in women and recipients of kidneys from female donors. High serum creatinine was a significant risk factor.
Conclusions:
- Posttransplant hyperuricemia is a common issue in elderly kidney transplant recipients.
- The study found a correlation between hyperuricemia and impaired renal allograft function.
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