Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endotracheal Tube Extubation

Endotracheal Tube Extubation

Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals.

Tracheostomy Decannulation

Tracheostomy Decannulation

Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...

Mechanical Ventilation I: Indication and Settings

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Ventilatory Modes

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intraoperative mechanical power and postoperative pulmonary complications: association and threshold analysis in adult intra-abdominal surgery.

Journal of anesthesia, analgesia and critical care·2026

Same author

High-Flow Nasal Cannula in Subjects Undergoing Endoscopy With Intravenous Sedation.

Respiratory care·2026

Same author

Randomized controlled trial of procedural sequence for same-day bidirectional endoscopy under monitored anesthesia care (RECoVER Trial).

iGIE : innovation, investigation and insights·2026

Same author

General anesthesia and/or deep hypnotic state in propofol-based conscious sedation for endoscopy.

iGIE : innovation, investigation and insights·2026

Same author

High-flow nasal cannula use for respiratory support in children for indications other than acute bronchiolitis.

The Cochrane database of systematic reviews·2026

Same author

Impact of Post-COVID syndrome on quality of life and mental health among COVID-19 survivors: A study from a tertiary care center in Lebanon.

Respiratory medicine·2025

Same journal

The evolution of nonoperating room anesthesia: navigating a new frontier.

Current opinion in anaesthesiology·2026

Same journal

Enhanced recovery pathways for patients with chronic pain: beyond standard protocols - a narrative review.

Current opinion in anaesthesiology·2026

Same journal

Novel technologies and innovations in postoperative follow-up after regional anesthesia.

Current opinion in anaesthesiology·2026

Same journal

Regional anaesthesia and analgesia in surgical patients with chronic preoperative pain: mechanisms, evidence, and clinical implications.

Current opinion in anaesthesiology·2026

Same journal

Retention in pain care and research: a narrative review focused on implanted medical devices.

Current opinion in anaesthesiology·2026

Same journal

Airway ultrasound in patients undergoing head and neck surgery.

Current opinion in anaesthesiology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 26, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

Weaning from mechanical ventilation.

Imad BouAkl¹, Pierre Bou-Khalil, Ghassan Kanazi

¹Division of Pulmonary & Critical Care, Department of Medicine, American University of Beirut, Beirut, Lebanon.

Current Opinion in Anaesthesiology

|December 7, 2011

Summary

This summary is machine-generated.

This review explores recent advances in mechanical ventilation liberation, focusing on readiness assessment, weaning failure causes, protocols, and noninvasive ventilation. The goal is a more scientific approach to expedite patient liberation safely.

More Related Videos

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

Related Experiment Videos

Last Updated: May 26, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats

A Structured Approach to Extubation in Mechanically Ventilated Rats

Published on: July 18, 2025

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

Area of Science:

Critical Care Medicine
Pulmonology
Respiratory Therapy

Background:

Mechanical ventilation liberation is a critical clinical decision with risks of early extubation failure or prolonged intubation complications.
Physicians face challenges in determining optimal timing for extubation.
Continuous improvement in tools and methods for assessing readiness is ongoing.

Purpose of the Study:

To review the latest studies on mechanical ventilation liberation.
To assist physicians in utilizing recent developments in the field.
To enhance the scientific approach to weaning and extubation.

Main Methods:

Literature review of recent studies on mechanical ventilation liberation.
Analysis of advances in readiness assessment and testing.
Evaluation of factors contributing to weaning failure.
Assessment of noninvasive positive pressure ventilation's role.

Main Results:

Recent advances in assessing and testing readiness for liberation from mechanical ventilation.
Identification of causes for weaning failure.
Demonstration of the value of weaning protocols.
Exploration of noninvasive positive pressure ventilation's utility in liberation.

Conclusions:

Recent findings are making the process of weaning and liberation more scientific.
This shift aims to expedite liberation from mechanical ventilation.
The objective is to reduce failure rates and patient risks.