Related Experiment Video
Updated: May 26, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Isolated septic arthritis of the hip secondary to Fusobacterium necrophorum
Yuan-Pin Hsu1, Shih-Hung Tsai, Ling-Yuan Li
1Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China. m871023@ndmctsgh.edu.tw
Abstract:
Septic arthritis secondary to Fusobacterium necrophorum is rare and may be related to Lemierre syndrome which classically presents as pharyngitis in young adults, followed by a septicemic illness characterized by internal jugular vein thrombosis and metastatic infection. However, there were only 5 case reports of isolated septic arthritis caused by F. necrophorum in previous literature. The authors reviewed the literature and report a 24-year-old woman who delayed presentation to the emergency department and was eventually diagnosed with isolated septic arthritis of the hip caused by F. necrophorum. Her condition was complicated by severe sepsis and treated with aggressive resuscitation, vasopressor, antibiotics and an open arthrotomy with repeated drainage. Eventually, her hip bone was destroyed and she required a joint replacement.
Insights
Fusobacterium necrophorum septic arthritis is rare, often linked to Lemierre syndrome. This case highlights isolated hip joint infection by this bacteria, leading to severe sepsis and hip replacement.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Septic arthritis caused by Fusobacterium necrophorum is uncommon, with only five prior case reports.
- Fusobacterium necrophorum is often associated with Lemierre syndrome, a condition involving pharyngitis, jugular vein thrombosis, and metastatic infection.
Observation:
- A 24-year-old female presented with delayed medical attention for isolated septic arthritis of the hip.
- The patient developed severe sepsis secondary to Fusobacterium necrophorum hip infection.
Findings:
- The patient required aggressive treatment including resuscitation, vasopressors, antibiotics, and surgical drainage via arthrotomy.
- Despite extensive treatment, the infection led to significant destruction of the hip bone, necessitating a total hip replacement.
Implications:
- This case underscores the potential for Fusobacterium necrophorum to cause isolated septic arthritis, even without typical Lemierre syndrome features.
- Delayed presentation and treatment can result in severe outcomes, including joint destruction and the need for joint replacement surgery.
- Highlights the importance of considering rare pathogens in septic arthritis, particularly in cases with severe sepsis or unusual presentations.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Bacterial Phylum Spirochaetes
Rheumatic Heart Disease I: Introduction
Bacterial Meningitis II: Pathophysiology
Brain Abscess l: Introduction