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Carnitine deficiency following massive intestinal resection: a morphological and biochemical study
H Miyajima1, M Sakamoto, T Oikawa
1First Department of Medicine, Hamamatsu University School of Medicine, Japan.
Japanese Journal of Medicine
|January 1, 1990
Summary
A patient with muscle weakness and liver issues after bowel surgery experienced carnitine deficiency. Supplementation improved symptoms and reduced lipid buildup, suggesting biosynthesis or dietary issues.
Area of Science:
- Biochemistry
- Muscle Physiology
- Nutritional Science
Background:
- Massive small bowel resection can lead to malabsorption and nutritional deficiencies.
- Carnitine plays a crucial role in fatty acid metabolism within muscle cells.
- Lipid accumulation in muscle fibers is indicative of metabolic dysfunction.